Development of approaches for stimulation of T-regulatory cells for immunotherapy of vitiligo [Text] : Dis. ... Dr. of philosophy (PhD) : 6D060700 - Biology / Z. Y. Mukhatayev ; scientific supervisors: Y. O. Ostapchuk ; al-Farabi Kazak National University... – Almaty : [s.n.], 2020. - 122p., ill. ; tabl.;+ 1 electronic optical disk (CD-ROM) . . – Bibliogr.: p. 102-119 . – [n. c.] : 5 tg.
The purpose of the research is to study the phenotypical characteristics of peripheral blood Tregs of patients with vitiligo and to develop approaches for stimulating and generating antigen-specific Tregs based on CAR, and assessing them in vitro and in vivo for a potential immunotherapy of vitiligo, as well as evaluating the effect of antibiotics to control depigmentation in a mouse model